Histopathology of Preclinical Toxicity Studies, Third Edition: Interpretation and Relevance in Drug Safety Evaluation
| Author | : | |
| Rating | : | 4.48 (513 Votes) |
| Asin | : | 0444527710 |
| Format Type | : | paperback |
| Number of Pages | : | 960 Pages |
| Publish Date | : | 2013-06-16 |
| Language | : | English |
DESCRIPTION:
This work covers effectively all aspects of drug-induced pathology that may be encountered within preclinical toxicity studies. It also contains many pertinent references to both human and animal pathology forming an essential basis for the assessment of drug-induced pathology. It fills a gap in the pathology literature relating to the preclinical safety assessment of new medicines. NEW TO THE THIRD EDITION:* Covers drug induced pathology in preclinical (animal) studies and their relevance for patients or volunteers in clinical studies* General comments to each chapter about the relevance of pathological findings to humans* Provides essential information that can help decide the relevance of particular lesions for patients. Numerous colour photographs are included that highlight and embellish the histopathological features that are described. Information relevant to understanding the nature of pathological changes in pre-clinical studies and assessment of their relevance to the clinical investigation of new drugs is also covered. It systematically describes, in one volume, both spontaneous and drug induced pathology on an organ by organ basis
MBChB, FRCPath, Consulting Pathologist and Honorary Senior Lecturer, Department of Cancer Studies and Molecular Medicine, University of Leicester, UK
About the Author MBChB, FRCPath, Consulting Pathologist and Honorary Senior Lecturer, Department of Cancer Studies and Molecular Medicine, University of Leicester, UK